Relationship between IndiyidualDifference in Melatonin Habitual Bedtime Suppression by Light and Shigekazu Higuchi ] L YIitaka Motohashii

نویسنده

  • Keita Ishibashi
چکیده

The purposc of this study was to determine rhe relationship bctwcen indiyidual difference in me]atonin suppression by cxposure to Light and habitual bedtimc. Seventeen hca]thy male students (mean age: 22,6± 2,4yr) volunteered to participate in the study, The sub.iects were exposcd to light (1OOO lx) for 2 hours from 2 hours befbre the time of pcak salivary meLatonin concentratien. 'two hours aftcr exposurc to the light, melatonin suppression had occurred in fifteen subjects. No significant correlation was found between the rate of melatonin suppression and habitual bedtime in the fifteen sub.jects in whom me]atonin suppression oceurred. Howover, the habitual bcdtime of thc two subjects in w'hom meLatonin suppression did not eccur was earlier than that of the other subjects. Thcse resu]ts suggest that there are some people with very ]ow scnsitivity to light and that this may affect habitual bcdtimc. J Ph.vsivt Anthropol Anpr Hztnian Sci 24(4)r 419-423, 200)http:/,iwww.jstage.jst.go,jp/browse・'jpa [DOI: 10.21 14"jpa.24.4191 Keyvvords: melatonjn suppression, light, sensitivity, bedtime. sleep habits, physiological po]ymorphism

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Influence of eye colors of Caucasians and Asians on suppression of melatonin secretion by light.

This experiment tested effects of human eye pigmentation depending on the ethnicity on suppression of nocturnal melatonin secretion by light. Ten healthy Caucasian males with blue, green, or light brown irises (light-eyed Caucasians) and 11 Asian males with dark brown irises (dark-eyed Asians) volunteered to participate in the study. The mean ages of the light-eyed Caucasians and dark-eyed Asia...

متن کامل

An ancestral haplotype of the human PERIOD2 gene associates with reduced sensitivity to light-induced melatonin suppression

Humans show various responses to the environmental stimulus in individual levels as "physiological variations." However, it has been unclear if these are caused by genetic variations. In this study, we examined the association between the physiological variation of response to light-stimulus and genetic polymorphisms. We collected physiological data from 43 subjects, including light-induced mel...

متن کامل

Effectiveness of a red-visor cap for preventing light-induced melatonin suppression during simulated night work.

Bright light at night improves the alertness of night workers. Melatonin suppression induced by light at night is, however, reported to be a possible risk factor for breast cancer. Short-wavelength light has a strong impact on melatonin suppression. A red-visor cap can cut the short-wavelength light from the upper visual field selectively with no adverse effects on visibility. The purpose of th...

متن کامل

The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: assessment in a clinical trial of melatonin replacement.

The present investigation used a placebo-controlled, double-blind, crossover design to assess the sleep-promoting effect of three melatonin replacement delivery strategies in a group of patients with age-related sleep-maintenance insomnia. Subjects alternated between treatment and "washout" conditions in 2-week trials. The specific treatment strategies for a high physiological dose (0.5 mg) of ...

متن کامل

Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans.

CONTEXT Millions of individuals habitually expose themselves to room light in the hours before bedtime, yet the effects of this behavior on melatonin signaling are not well recognized. OBJECTIVE We tested the hypothesis that exposure to room light in the late evening suppresses the onset of melatonin synthesis and shortens the duration of melatonin production. DESIGN In a retrospective anal...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017